Purpose /Significance Diversified development of industry is conducive to the dispersion of external shocks, maintaining of economic stability, and promotion of regional industrial restructuring and regional coordinated development.

Method/Process This paper uses the entropy method to decompose industrial diversification into related diversification and irrelevant diversification, and explores the spatial differences and influencing factors heterogeneity of regional industrial diversification.

Results/Conclusions The study findsout that the diversified development of China's regional industries shows regional distribution characteristics, which is opposite to the difference in economic development between the east, central and western regions.Some economic factors clearly show the "prone" influence of coastal provinces, among which the industry externality, human capital, relative urbanization level, informatization, infrastructure, financial development, technology level, and openness have a stronger impact on industrial diversification in the eastern region than in the central and western regions.Economic factors and policy factors have opposite effects on related diversification and unrelated diversification. Government intervention has inhibited the diversification of industrial development in the central and western regions, but it can promote the diversified development of coastal provinces. The municipality has the geographical advantage of diversified industrial development.