Synthesis of Imidazole Chiral Ionic Liquids Derived from Proline and Its Application in Asymmetry Micheal Reaction

Ionic liquid (IL) has many advantages, such as high chemical stability and solubility, low toxicity, low volatile, non-combustible, recyclable etc. Natural amino acid is a kind of chiral source molecules, and L-proline is the star molecules because it reveals the organocatalysis prelude. In view of these, we synthesized a novel imidazole chiral ionic liquid with L-proline as chiral source. This new chiral ionic liquid was applied to catalyze the asymmetric Micheal addition. The results show that this imidazole chiral ionic liquid derived from proline has good asymmetric catalytic and recycling performance.