Abstract: Based on the panel data of eastern China from 2010 to 2019, this paper calculates the digital economic efficiency and finds that there are great differences in both static section efficiency and dynamic inter-temporal efficiency. In terms of static section efficiency, Liaoning and Hainan Provinces have the highest efficiency and reach the forefront of technical efficiency, while Guangdong Province has the lowest technical efficiency. The results of inter-temporal efficiency changes from 2018 to 2019 show that except Liaoning, Hainan and Fujian, the technical efficiency of other 8 provinces and cities has decreased, and the scale efficiency is the main reason for the decline of technical efficiency. In order to promote the high-quality development of digital economy and improve the regional efficiency of digital economy, it is necessary to promote the digital transformation support policies in the eastern areas; to give birth to new technologies, new capital, new labor, new land and new ideas, and to optimize resource investment in digital economy construction; to strengthen scientific and technological innovation, and to build a new pattern of double circulation; to give play to its own advantages, and to create a new model for the development of digital economy.