Abstract: Rui-an literary school is an important school in the history of the academic development in the Qing Dynasty and the Chinese academy of history. Cui Xuepeng, Kong Zhaoxin, Ma Junwu, Song Cibao had referred to the Rui-an school, but the origin of Rui-an school of is unknown. This paper argues that the academic development from the mid Ming Dynasty to the Qing Dynasty, literary inquisition and "Si Ku Quan Shu" classics writing and imperial examination system, the development of academies of classical learning are the era background driving factors for the the formation of the Rui-an school. And the family blood, affinity, and the teacher-freind communication are the accelerators.